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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWWP2A
All Species:
3.64
Human Site:
S643
Identified Species:
10
UniProt:
Q96N64
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96N64
NP_001124336.1
755
81960
S643
K
V
F
S
K
N
V
S
K
C
V
T
P
D
G
Chimpanzee
Pan troglodytes
XP_527102
538
59830
K427
V
F
S
K
N
V
S
K
C
V
T
P
D
G
R
Rhesus Macaque
Macaca mulatta
XP_001092260
513
55832
E402
L
H
T
Q
S
V
S
E
C
I
T
E
D
G
R
Dog
Lupus familis
XP_853285
538
59617
K427
V
F
S
K
N
V
S
K
C
V
T
P
D
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z61
730
79369
N616
K
M
K
I
F
S
K
N
V
S
K
C
I
T
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506246
617
69027
K506
V
F
S
K
N
V
S
K
C
V
T
P
D
G
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687488
955
103666
T843
A
V
F
S
K
N
V
T
K
C
V
A
L
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395213
680
75929
D569
T
A
N
G
R
R
M
D
V
G
D
V
V
W
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796495
568
61717
L455
K
N
V
T
K
S
I
L
P
G
G
R
T
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.1
28.4
69
N.A.
85.3
N.A.
N.A.
71.1
N.A.
N.A.
48.6
N.A.
N.A.
20.7
N.A.
24.5
Protein Similarity:
100
71.2
43.8
70.4
N.A.
89.6
N.A.
N.A.
77.4
N.A.
N.A.
60
N.A.
N.A.
37.6
N.A.
38.6
P-Site Identity:
100
0
0
0
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
73.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
0
0
0
N.A.
26.6
N.A.
N.A.
0
N.A.
N.A.
80
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
45
23
0
12
0
0
12
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
12
0
45
23
0
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% E
% Phe:
0
34
23
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
23
12
0
0
45
34
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
12
0
0
12
0
0
12
0
0
% I
% Lys:
34
0
12
34
34
0
12
34
23
0
12
0
0
0
0
% K
% Leu:
12
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% L
% Met:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
12
0
34
23
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
0
34
12
0
12
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
12
0
0
0
0
0
12
0
0
45
% R
% Ser:
0
0
34
23
12
23
45
12
0
12
0
0
0
0
0
% S
% Thr:
12
0
12
12
0
0
0
12
0
0
45
12
12
12
0
% T
% Val:
34
23
12
0
0
45
23
0
23
34
23
12
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _